How to call Server Side function from Client Side Code

You cannot call server-side code ‘directly’ from client-side code. That is because by design, the server side code executes at server side and client side code at the client. However there are some workarounds.
1. Use __doPostBack() and IPostBackEventHandler.
2. Set hidden variables and sumbit the form using form.submit()
3. Use PageMethods in ASP.net AJAX.

PageMethods can possibly save you a large amount of bandwidth which can mean faster response times for visitors on slower connections. Instead of posting all of the form values, we can send only what is needed. Instead of returning a large chunk of data, we can return precisely what we need to display to the user. For performance and bandwidth sensitive situations, they may be the right tool. So use PageMethods where possible instead of UpdatePanel as UpdatePanel posts all of the page's form values when all you might need to pass to the server is very little information. Using PageMethods you can save bandwidth.

Here is a link to learn how to use PageMethods: http://www.dotnetcurry.com/ShowArticle.aspx?ID=109